Holy Oplexan-125ml

Features and benefits of OPLEXAN:
• Vitamin A:
 Retinol, a fat soluble vitamin, is essential to the differentiation of epithelial cells and the maturation of keratocytes and so the formation of the keratinous layer.
 As a consequence, retinol deficiency causes a general keratinization problem, with scaling. These problems were associated with visual deficiencies and digestive problems (Scott et al, 2001).
 Regulates the growth of epidermal cells and the production of sebum. It helps combat seborrhea and the pellicles that often form after a pruritic episode. It acts in synergy with zinc and sulfated amino acids.
 Normalizes leptin blood concentration.
 Cats are unable to convert B-carotene from plants to vitamin A and thus need to receive preformed vitamin A
• Vitamin D3
 Calcitriol production is regulated at the level of the 1-a-hydroxylase enzyme in the kidney. Phosphate in excess and loss of functional renal mass result in a decrease in 1-a-hydroxylase activity and reduces the conversion of 25-dihydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 (calcitriol).
 Calcitriol deficiency reduces the intestinal absorption of calcium, reduces the release of calcium and phosphate from bone, reduces renal reabsorption of calcium and phosphate and increases the synthesis and release of PTH.
• Vitamin E
 Vitamin E is actually a natural antioxidant, being consumed during oxidation.
 An experimental deficiency in dogs provokes the appearance of dry seborrhea, diffuse alopecia, erythroderma, secondary pyoderma and anomalies of the immune system.
 A vitamin E supplement helps protect PUFA’s from oxidation.
 Vitamin E supplementation can reduce free radical or oxidant injury in many types of liver disease and may prevent progression of disease.
• Vitamin K:
 Deficiency of vitamin K leads to coagulopathy disorders.
 Vitamin B12, vitamin E, vitamin K and vitamin A deficiencies are very common in dogs suffering from exocrine pancreatic insufficiency (EPI).
• Vitamin B12
 Vitamin B12 plays a fundamental role in protein synthesis and red blood cell production and has an enzyme function in many essential biochemical reactions.
 Vitamin B12 also combats aging.
• Vitamins B1, B2 and B6:
 Water soluble vitamins play a role as coenzymes for the cellular enzymes involved in energy metabolism and tissue synthesis.
• Niacin:
 Niacin (or nicotinamide) is synthesized from tryptophan. It is essential for cellular respiration.
 With deficiency, dermatitis of the abdomen and the hind limbs occurs in dogs.
• Biotin:
 Vitamin H is essential to skin integrity.
 Biotin deficiency can lead to mild or severe hair loss.
• Folic acid:
 Plays an essential role in the synthesis of nucleic acids (in synergy with Cobalamin).
 A deficiency disrupts protein synthesis, especially for fast-regenerating tissues like hematopoietic tissue.
• Zinc:
 Zinc is an essential trace metal involved in many metabolic and enzymatic functions of the body.
 Zinc benefits the urea cycle and central nervous system neurotransmission, has clear Hepato-protective effects against a variety of hepatotoxic agents, and has antioxidant functions.
 Zinc is essential to cell replication and proliferation.
 Zinc deficiency is associated with delayed wound healing and integumentary disorders.
• Calcium:
 Young animals have a high requirement for calcium to mineralize newly formed cartilage and osteoid.
 Deficiency in calcium leads to Hyperparathyroidism and pathological fractures.
• Pectin:
 Soluble fiber for GIT health.
 Intestinal demulcent with anti- diarrheal property.