Joint Care

Features and benefits of JOINTCARE:
1. Bowsellic acid
• Boswellic acid (BA), a series of pentacyclic triterpene molecules, is isolated from the gum resin of Boswellia serrata and Boswellia carteri.
• Boswellic acid proved to be one such agent that has exhibited efficacy against various chronic diseases like arthritis
• A standardized Boswellia resin extract with well documented quality and stability could be recommended as a safe herbal dietary supplement for dogs, providing symptomatic relief in osteoarthritic disease (1)
2. Procyanidine
• Procyanidins are a family of plant metabolites that have been suggested to mitigate osteoarthritis pathogenesis in mice
• Procyanidins mitigate osteoarthritis pathogenesis, which is mediated, at least in part, by suppressing vascular endothelial growth factor signaling. (2)
3. Turmeric extract
• Curcuma longa or turmeric is an Ayurvedic herb that has been traditionally used to treat inflammatory conditions like rheumatoid arthritis.
• The administration of Curcuma longa extract arrests the degenerative changes in the bone and joints of collagen-induced arthritic rats. (3)
4. Cinnamaldehyde
• Cinnamaldehyde suppresses IL-1β-induced inflammation in synoviocytes through the JAK/STAT pathway
• Cinnamaldehyde also alleviate collagen-induced arthritis in rats. (4)
• Cinnamaldehyde has potent antioxidant properties so it could be used as an adjunct in the management of rheumatoid arthritis (5).
5. Glucosamine and Chondroitin sulfate
• Glucosamine and chondroitin are commonly recommended by veterinarians as an alternative for treating osteoarthritis in canines unable to tolerate the adverse effects of NSAIDs, or as add-on therapy. (6)
• Abundant basic science evidence (biochemical, cell culture, tissue culture, animal models of arthritis) suggests that glucosamine and chondroitin sulfate should be beneficial in the treatment of osteo- arthritis. A growing body of veterinary and human clinical evidence shows that they are effective in reducing the symptoms of arthritis in both animals and humans. (7)
6. Methylsulfonylmethane
• Methylsulfonylmethane (MSM) is a naturally occurring organic from of sulphur used primarily as an anti-inflammatory and antioxidant for conditions such as arthritis and some cancers.
7. Hyaluronic acid
• Hyaluronic acid is a natural substance found in the fluids in the eyes and joints. It acts as a cushion and lubricant in the joints and other tissues.
• Hyaluronic Acid plays two important roles in dogs:
 Lubrication The sticky fluid provides great lubrication for the hip and joints.
 Shock Absorption The fluid acts as a shock absorber and reduces potential inflammation
8. Omega3
• Omega-3 fatty acids help reduce inflammation throughout the body, including in the joints.
• This can help to decrease the pain and stiffness associated with conditions like arthritis. Omega-3 fatty acids can also help protect joint tissue from further damage.
9. Di calcium phosphate
• Source of calcium and phosphorous for bone health.
10. Vitamin C
• Vitamin C plays a critical role in the maintenance of a normal mature collagen network by preventing the auto-inactivation of lysyl and prolyl hyroxylase, two key enzymes in collagen biosynthesis.
• So, vitamin C is good for slowing degenerative joint diseases, hip dysplasia, and spinal disorders.
• Vitamin C is also a preventative and immune booster by acting as natural antioxidant.
11. Selenium (sodium selenite) & Zinc (zinc oxide)
• Selenium and zinc are natural antioxidants and non-specific immunostimulants.
• Zinc plays an important role in many substances in the canine body, including enzymes, proteins, and hormones. Zinc is also important for immune system function and thyroid function.
• Zinc deficiency can result in many problems for dogs, including: Lack of protection from infection
• Selenium regulates the functions of general metabolism including normal thyroid activity, and is also an antioxidant involved in DNA synthesis, reproduction, and the immune system
• Selenium is essential for optimum bone health
12. Manganese (manganese oxide) & Magnesium (magnesium oxide)
• Dogs need manganese to produce energy, metabolize protein and carbohydrates, and to make fatty acids.
• Manganese is an important part of many enzymes and plays a role in the health and maintenance of bone and cartilage in joints
• Magnesium is involved with energy production at the cellular level. Every time your pet moves a muscle, experiences a heartbeat, or has a thought, magnesium is needed to facilitate that transfer of energy.
• Also magnesium involved in functioning of are three other minerals: sodium, potassium, and calcium.
13. Lysine & L-Methionine
• Lysine and methionine are essential amino acids for dogs and cats
• Methionine is approved as a treatment for urinary stones in dogs. Methionine is a urine acidifier, so it can prevent the formation of struvite stones which are caused by an overly high alkaline content in the urine.
• L-Lysine is an essential amino acid that helps your pet’s body produce antibodies, hormones, and enzymes that boost the immune system.
• L-Lysine also helps with calcium absorption (for strong bones) and collagen production (for healthy skin)